Drug test sieve

Thursday February-27 2025  11:11:01

Drug test sieve is a screening device specially used in drug research and production. It is mainly used for particle size analysis, grading and impurity removal of drug raw materials, intermediates and finished products to ensure the quality and efficacy of drugs. It is widely used in pharmaceutical, chemical, food and other industries.

Video of drug test sieve

How does the drug test sieve work?

Drug test sieves are basically the same as ordinary screening equipment, both of which use the aperture size of the sieve to separate materials of different particle sizes. The difference is that drug test sieves usually have higher precision and stricter quality control standards to meet the special requirements of drug production.

What types of drug test screens are there?

How to use the drug test sieve

1. Preparation: Select the sieve of appropriate size and stack them in order from large to small mesh. Prepare the receiving tray and lid to ensure that the sieve group is firmly installed.

2. Sample processing: Take a representative drug sample, dry it and weigh it. If the sample is agglomerated, it needs to be crushed or dispersed in advance.

3. Sieving operation: Pour the sample into the top sieve. Gently shake the sieve group to allow the drug particles to pass through the sieve holes. Use a vibrating sieve machine and set the time (usually 5-15 minutes) for automatic sieving.

4. Collection and weighing: After the sieving is completed, remove the sieves layer by layer and collect the drug particles on each layer of the sieve. Use a balance to weigh the mass of each layer of drug particles and record the data.

5. Data analysis: Calculate the mass percentage of each particle size interval. Draw a sieving curve and analyze the drug particle size distribution.

The structure of the drug test sieve

Drug test sieve is mainly composed of three parts: the screen frame, the screen mesh and the chassis.

Screen frame: usually made of stainless steel, with good corrosion resistance and wear resistance. The diameter and height of the screen frame are selected according to needs.

Screen mesh: The screen mesh is the core component of screening and is woven from metal wire or nylon wire. The aperture size of the screen mesh is selected according to needs, and high precision is required.

Chassis: used to collect materials passing through the screen mesh.

What can drug test sieves be used for?

1. Drug raw material screening: In the drug research and development stage, researchers need to screen various drug raw materials and select suitable raw materials for the preparation of new drugs. Drug test sieves can help screen out particles that meet the requirements and ensure the quality and purity of the raw materials.

2. Intermediate screening: In the drug production process, intermediates need to be screened to remove impurities or unnecessary particles to ensure the purity and stability of intermediates.

3. Finished drug quality control: In the final stage of drug production, finished drugs need to be quality controlled, including parameters such as particle size and shape. Drug test sieves can help test the particle characteristics of finished drugs and ensure that the product meets the specified quality standards.

4. Solvent screening: In drug production, solvents often need to be screened to remove impurities or solid particles, ensure the purity of the solvent, and avoid affecting the quality of the drug.

Precautions for drug test sieves

Screen selection: Choose the appropriate screen size according to the drug particle size range. The screen material needs to be wear-resistant and corrosion-resistant (such as stainless steel).

Sample volume control: The sample volume should not be too large to avoid affecting the screening efficiency. Too little sample volume may result in unrepresentative data.

Screening time: The screening time must be sufficient to ensure that the drug particles are fully graded. Too short may result in incomplete screening, and too long may cause particle damage.

Screen cleaning: The screen needs to be thoroughly cleaned before and after screening to prevent blockage or cross contamination.

Repeated testing: To improve accuracy, it is recommended to perform multiple tests and take the average value.

Drug test sieve is an efficient and multifunctional screening equipment, which is widely used in pharmaceutical, chemical, food and other industries. Through reasonable selection, correct use and regular maintenance, its performance advantages can be fully utilized to meet the screening needs of different materials.